Medical University of Warsaw is the largest and the oldest, most prestigious medical school in Poland. We are part of the Faculty of Medicine, Department of Biochemistry.
Karolinska Institute is the largest medical university in Sweden and is ranked among the top medical universities in the world. We are part of the Department of Oncology-Pathology.
A novel allosteric mechanism of p53 reactivation for improved cancer therapy.
Unlike others, we target the N-terminal region of p53 pharmacologically to trigger the allosteric shift in p53 and prevent it from interactions with MDM2 and MDM4.
Research on drug repurposing for the improved therapy in TP53-mutated AML awarded.
We discovered previously overlooked correlations between specific amino acid deviations in p53 and the lifespans across species in Animal Kingdom. Species with extended lifespans have certain characteristic amino acid substitutions in the p53 DNA-binding domain that alter p53 function. Welcome to read more here
We are starting a new Lab at the Medical University of Warsaw (MUW/WUM).