The Medical University of Warsaw is the largest and the oldest, most prestigious medical school in Poland. We are part of the Faculty of Medicine.
Karolinska Institute is the largest medical university in Sweden and is ranked among the top medical universities in the world. We are part of the Department of Oncology-Pathology.
We have published a novel allosteric mechanism of p53 reactivation for improved cancer therapy.
Unlike others, we target the N-terminal region of p53 pharmacologically to trigger the allosteric shift in p53 and prevent it from interactions with MDM2 and MDM4.
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June 27, 2022
We have published a new review article about mutTP53 and mutEGFR NSCLC in IJMS MDPI.